
Overview of Wilson disease manifestations
Wilson disease can affect multiple organ systems, including:1-3
- Hepatic
- Neurologic
- Psychiatric
- Ophthalmologic
- Cardiovascular
- Cutaneous
- Hematologic
- Renal
- Gynecologic
- Musculoskeletal
Read on to learn more about the most common manifestations seen in patients with Wilson disease.
- Hepatic dysfunction: reported as the initial clinical manifestation in ~45% of patients10,11
- Neurologic dysfunction: reported as the initial clinical manifestation in ~40−60% of patients1,10
- Psychiatric manifestations: reported to affect 30−40% of patients at diagnosis12
- Kayser–Fleischer rings: present in 10−90% of patients8